how to use epinephrine auto-injector

Each single-dose epinephrine auto-injector is designed to provide accurate delivery of epinephrine when it's needed most.

 

Self-Administration Video

 

 

Caregiver Administration Video

 

Before you use your epinephrine auto-injector, make sure the medicine is ready when you need it. Look at it regularly, and if the medicine in the epinephrine auto-injector is cloudy, discolored, has particles in it, or if the expiration date has passed, the epinephrine auto-injector should be replaced.4 Follow the color-coded instructions on the device.

Do NOT remove GRAY caps until you are ready to use the epinephrine auto-injector.4

The following instructions should be followed for both epinephrine auto-injector 0.15 mg and epinephrine auto-injector 0.3 mg.4

visual administration instructions for epinephrine auto-injector

Avoid injecting into buttock or any other part of your body.

After use/disposal:

Your epinephrine auto-injector is designed to contain more medicine (liquid) than what is delivered in a dose. After using the device, there will be extra liquid remaining in the auto-injector. This is a normal function of the auto-injector.4

  • The remaining liquid that is left after this fixed dose cannot be further administered and should be discarded.4
  • Put the auto-injector, needle first, into the carrying case.4
  • Put the light gray case top over the non-needle end of the epinephrine auto-injector unit and close the case.4
  • Give your used epinephrine auto-injector to a healthcare worker for proper disposal. Do NOT throw away in a regular trash can.4

These instructions for disposal are also contained in the Patient information leaflet and on this website in the section titled Disposal of epinephrine auto-injector.

  • Tips for using epinephrine injection, USP auto-injector
    • Do NOT remove the gray caps until you are ready to use the epinephrine auto-injector.4
    • Never put thumbs, fingers, or hand over the red tip. The needle comes out of the red tip. Accidental injection into hand or feet may result in the loss of blood flow to these areas. If this happens, go immediately to the nearest emergency room.4
    • Keep your epinephrine auto-injector at room temperature: 68°-77°F (20°-25°C) with excursions permitted to 59°-86°F (15°-30°C). Do not refrigerate or freeze.10
    • Check your epinephrine auto-injector regularly. Replace it if it has expired, or if the medicine is cloudy, discolored, or has particles in it.4
    • Keep your epinephrine auto-injector with you at all times.4
  • Storage of epinephrine auto-injector
    • The medicine in your epinephrine auto-injector can deteriorate when exposed to light, so keep it in the protective carrying case provided.4
    • The medicine in your epinephrine auto-injector can also deteriorate when exposed to heat; for example, do not keep it in your car.10
    • Keep your epinephrine auto-injector at room temperature: 68°-77°F (20°-25°C) with excursions permitted to 59°-86°F (15°-30°C). Do not refrigerate or freeze.10
    • Your epinephrine auto-injector is marked with an expiration date. You should periodically check your epinephrine auto-injector to make sure it has not expired. If it has, you should dispose of it and get a replacement.4
    • You should also periodically check to make sure the medicine in your epinephrine auto-injector is not cloudy, discolored, or has particles in it. If it does, you should dispose of it and get a replacement.4
    • NOTE: The epinephrine auto-injector is not waterproof, so if it is ever submerged in water or any other liquid, it cannot be used. If this occurs, obtain a replacement.

  • Disposal of epinephrine auto-injector

    After using your epinephrine auto-injector, the remaining medicine in the epinephrine auto-injector cannot be further administered and should be discarded. Give your used epinephrine auto-injector to a healthcare worker for proper disposal. Do NOT throw away in a regular trash can.4

  • Accidental administration

    In the case of accidental injection, go immediately to the nearest emergency room.4

Click here to view the full reference list.

how to use epinephrine auto-injector
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Indication

Important Safety Information

Click here for full Prescribing Information for epinephrine injection, USP auto-injector.

For more information about epinephrine injection, USP auto-injector, ask your doctor or call 1-888-894-6528. Ask your doctor if epinephrine injection, USP auto-injector is right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Go to www.FDA.gov/medwatch or call 1-800-FDA-1088.

Indication

  • Epinephrine auto-injector is an emergency injection ("shot") of epinephrine. It is a medicine used for life-threatening allergic reactions such as severe swelling, breathing problems, or loss of blood pressure. Allergic reactions can be caused by stinging and biting insects (bugs), allergy injections, food, medicines, exercise, or unknown causes.
  • After using epinephrine auto-injector go to your doctor or emergency room right away for more medical treatment.

Important Safety Information

  • Make sure to tell your doctor about all your medical conditions and allergies, but especially if you:
    • have heart disease or high blood pressure
    • have diabetes
    • have thyroid conditions
    • have asthma
    • have depression or other mental disease
    • have Parkinson's disease
    • are pregnant
    • are allergic to any of the ingredients in epinephrine auto-injector
  • Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Some medicines may cause serious side effects if taken while you use epinephrine auto-injector. Some medicines may affect how epinephrine auto-injector works, or epinephrine auto-injector may affect how your other medicines work. Diabetic patients may need to adjust the dose of their diabetes medicines or insulin after using epinephrine auto-injector.
  • Avoid injecting epinephrine auto-injector into your buttock or any other part of your body, other than the middle of the outer side of your thigh (upper leg). Avoid injecting epinephrine auto-injector into a vein.
  • Too much epinephrine (epinephrine auto-injector) can cause dangerously high blood pressure, stroke, or death. If you take certain medicines, you may develop serious life-threatening side effects from the epinephrine in epinephrine auto-injector. Be sure to tell your doctor about all the medicines you take, especially medicines for asthma.
  • Patients with certain medical conditions, or who take certain medicines, may get more side effects from epinephrine auto-injector, or the side effects may last longer. This includes patients who take certain types of medicines for asthma, allergies, depression, hyperthyroidism, high blood pressure, and heart disease. Patients with heart disease may feel chest pain (angina). Patients with mental disease or Parkinson's disease may have worsening symptoms of their illness. Epinephrine auto-injector (epinephrine) can cause the following reactions. Some reactions can be serious. They usually go away with rest.
    • faster, irregular (wrong) or "pounding" heartbeat
    • throbbing headache
    • paleness
    • feelings of over excitement, anxiety, or fear
    • weakness or shakiness
    • dizziness
    • nausea and vomiting
    • sweating
  • These are not all the possible side effects of epinephrine auto-injector. For more information, ask your doctor or pharmacist.
  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
  • After use/disposal
    • The remaining liquid that is left after this fixed dose cannot be further administered and should be discarded.
    • Put the auto-injector, needle first, into the carrying case.
    • Put the light gray case top over the non-needle end of the epinephrine auto-injector unit and close the case.
    • Give your used epinephrine auto-injector to a healthcare worker for disposal. Do NOT throw away in a regular trash can.

Click here for full Prescribing Information for epinephrine injection, USP auto-injector.

For more information about epinephrine injection, USP auto-injector, ask your doctor or call 1-888-894-6528. Ask your doctor if epinephrine injection, USP auto-injector is right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Go to www.FDA.gov/medwatch or call 1-800-FDA-1088.